脂肪細胞の褐色化について
寒冷刺激は皮下脂肪中の常在T細胞からIL4を分泌させそれが脂肪細胞中のUCP-1を増加させている
the role of mucosal-associated invariant T (MAIT) cells in the regulatory mechanism of adipose browning.
Cold stimulation promotes interleukin-4 secretion by mucosal-associated invariant T cells in the adipose tissue to promote adipose browning in mice
LBP is identified as a negative regulator of the browning process, which is likely to contribute to the obesity-promoting action of LBP. The deleterious metabolic effects of LBP deletion are compatible with the concept that the appropriate regulation of inflammatory pathways is necessary for a healthy systemic metabolic profile, regardless of body weight regulation.
Lipopolysaccharide-binding protein is a negative regulator of adipose tissue browning in mice and humans
菌体成分であるリポポリサッカライドに結合する蛋白があると脂肪が減りにくい