リウマチの皮膚病変について
Rheumatoid arthritis is a chronic systemic disease that, in addition to articular involvement, may exhibit a variety of extraarticular manifestations.
The skin is frequently involved mainly in the most severe forms of the disease.
Rheumatoid nodules, accelerated rheumatoid nodulosis, rheumatoid nodulosis, Felty syndrome, rheumatoid vasculitis, pyoderma gangrenosum, rheumatoid neutrophilic dermatosis, interstitial granulomatous dermatitis, and palisaded neutrophilic granulomatous dermatitis are reviewed both clinically and histologically.
Moreover, cutaneous reactions related to treatments of rheumatoid arthritis, in particular to biologic agents, are described. Early recognition of these entities through a clinical and histological correlation permit to optimize the management of patients.
- 蝶形紅斑、円板状皮疹、口腔潰瘍、脱毛(全身性エリテマトーデス)
- 環状紅斑(シェーグレン症候群)
- 皮膚硬化(全身性強皮症)
- レイノー現象(手指の皮膚が白く冷たくなる)
- ゴットロン徴候、ゴットロン丘疹、ヘリオトロープ疹、爪囲紅斑(皮膚筋炎)
- ソーセージ様手指(混合性結合組織病)
- 点状出血や紫斑(悪性関節リウマチ/リウマトイド血管炎)
- 網状皮斑、隆起性紅斑(悪性関節リウマチ/リウマトイド血管炎)
- 皮下結節(関節の周り、肘、後頭部、おしりの骨の所によくみられるグリグリとした結節)
サルコイドーシス
強皮症